Pentaglobin use in dogs with primary immune-mediated hemolytic anemia (IMHA)
Researchers evaluated fourteen client-owned dogs diagnosed with primary IMHA at specialist referral hospitals in the United Kingdom.
All dogs received prednisolone, dexamethasone or both along with clopidogrel. Patients were randomized to receive Pentaglobin at 1 g/kg on up to 2 occasions, or to serve as controls. No other immunosuppressive drugs were allowed within the first 7 days of treatment.
Ten of 11 dogs from the treatment group and 2 of 3 dogs from the control group achieved remission and survived until hospital discharge. Survival and time to remission were not significantly different between groups.
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