Risk of severe sepsis from feline oral bacteria in hemodialysis patients

Capnocytophaga canimorsus is a commensal organism colonized in oral flora of dogs and cats and causes severe sepsis through bite wound in immunocompromised patients. To date, hemodialysis has not been reported as a risk of C. canimorsus infection.

A 75-year-old woman with end-stage renal disease secondary to hypertension suddenly developed septic shock. She lived with six cats in her home, but no bite or scratch wound was found on her body. She was empirically treated with piperacillin-tazobactam and temporally received continuous hemodiafiltration.

On the fifth day after sampling, blood culture revealed C. canimorsus as the cause of sepsis. After four weeks of antibiotic therapy targeting this organism, she recovered from the sepsis and was discharged on her 109th day of hospitalization.

Hemodialysis patients may be vulnerable to invasion into the blood stream by C. canimorsus due to the presence of punctures in their skin and the impaired immune function associated with uremia. Physicians should consider this organism as a cause of sepsis in hemodialysis patients who live with dogs or cats even in the absence of apparent bite wounds.

Read more on this article below:

Risk of severe sepsis from feline oral bacteria in hemodialysis patients