Evidence of Ebola virus exposure in dogs in Liberia
Filoviruses such as Ebola virus (EBOV) cause outbreaks of viral hemorrhagic fevers. The 2014-2016 EBOV outbreak in West Africa infected approximately 30,000 people, killing more than 11,000 and affecting thousands more.
In communities, dogs are often in contact with people. Researchers consider dogs to be sentinel animals for seroprevalence studies of emerging infectious viruses.
Researchers used a multiplex Luminex-based microsphere immunoassay (MIA) to detect dog IgG binding to recombinant filovirus antigens or LASV glycoprotein (GP) in serum from dogs. Potential exposure to filoviruses was identified 47 (73%) of 64 dog serum samples and up to 100% of the dogs from some communities were found to have elevated levels of EBOV antigen-binding IgG titers.
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