How overfeeding cats can effect on fatty acid distribution and metabolism
Researchers studied the effects of overfeeding cats. Eight cats were in the study. Four cats were fed twice their daily energy requirement with a commercial diet for 4 weeks. The control group was fed the estimated daily energy requirement with the same diet. Body weight, feline body mass index, body condition score, and plasma metabolites/hepatic injury marker were measured in all the cats before and after the experiment. Fatty acid profiles in the liver and subcutaneous adipose tissue were also measured.
After 4 weeks of overfeeding, the experimental group demonstrated significant increases in hepatic C18:1, plasma triglyceride, and nonesterified fatty acid (NEFA) concentrations and in alanine aminotransferase activity. The hepatic SCD-1 indices were positively correlated with body weight, feline body mass index, body condition score, and plasma NEFA concentration, although subcutaneous adipose tissue did not demonstrate any increase in SCD-1 indices in this study.
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