Altered microRNA Profiles and Associated Pathways in Canine Mammary Adenocarcinoma

Canine mammary tumors remain one of the most common neoplastic diagnoses in intact female dogs, and they continue to challenge clinicians with their biological diversity and unpredictable behavior. Among these tumors, mammary gland adenocarcinoma stands out for its aggressive nature and clinical relevance. Beyond their impact on canine health, these tumors also offer a powerful comparative model for human breast cancer. A recent study exploring microRNA expression in canine mammary adenocarcinoma adds a fresh molecular layer to this conversation and it is surprisingly relatable to what we already know from human oncology.