Mechanistic Insights into Feline Hypertrophic Cardiomyopathy: Pathway Analysis Highlights Age and Sex Differences

This article summarizes a study investigating molecular mechanisms in feline hypertrophic cardiomyopathy (HCM) via pathway analysis of cardiomyocyte markers. The study highlights age-related declines in gene expression, increased marker levels in HCM-affected cats, and significant sex differences with males showing higher expression. Findings emphasize continuous myocardial adaptation and the role of age and sex in disease pathogenesis. Keywords include feline HCM, cardiomyocyte gene expression, age and sex in cat heart disease, and molecular pathogenesis of feline cardiomyopathy.