Vet Candy Watch: Blue Pigs, Heavy Metal Water, and the Genetics of Feline HCM
This week on Vet Candy Watch, host Jeremiah Pouncey explores the latest veterinary science headlines that range from the genuinely puzzling to the downright bizarre. From unraveling the complicated genetics behind feline heart disease to investigating some truly strange blue pigs, this episode covers it all. Joining the conversation is veterinary cardiologist Dr. Hayley McDonald, who breaks down the science behind Felicyn CA-1 by PRN Pharmacal, the newly FDA conditionally approved drug for cats with hypertrophic cardiomyopathy.
Mechanistic Insights into Feline Hypertrophic Cardiomyopathy: Pathway Analysis Highlights Age and Sex Differences
This article summarizes a study investigating molecular mechanisms in feline hypertrophic cardiomyopathy (HCM) via pathway analysis of cardiomyocyte markers. The study highlights age-related declines in gene expression, increased marker levels in HCM-affected cats, and significant sex differences with males showing higher expression. Findings emphasize continuous myocardial adaptation and the role of age and sex in disease pathogenesis. Keywords include feline HCM, cardiomyocyte gene expression, age and sex in cat heart disease, and molecular pathogenesis of feline cardiomyopathy.