Genetic test detects early signs of kidney disease in cats
dapted from the original article by the Washington State University College of Veterinary Medicine, July 31, 2025
A newly developed genetic test now enables cat owners and veterinarians to detect the risk of chronic kidney disease (CKD) in felines years before symptoms develop, potentially extending the lifespan and quality of life for affected cats.
Created by researchers at Washington State University’s (WSU) College of Veterinary Medicine, the test—called Feline Apoptosis Inhibitor Macrophages (FAIM)—identifies a specific genetic variation that compromises a cat’s ability to produce a key protein responsible for kidney repair. This early detection tool is designed to identify cats genetically predisposed to progressive CKD, a condition that affects nearly 30–50% of cats over the age of 11 and can result in kidney failure, cardiovascular disease, anemia, and hypertension.
The FAIM test is processed through droplet digital PCR, a highly sensitive DNA testing method. Once available online via WSU’s Program in Individualized Medicine (PrIMe), the test will involve a simple at-home cheek swab that cat owners can mail to the WSU service center for analysis.
Early detection of CKD gives pet owners a critical window to make proactive lifestyle changes for their cats, such as modifying diet and avoiding medications that could accelerate kidney damage. While there is currently no cure for CKD, slowing its progression can reduce the long-term burden of the disease and potentially delay the need for expensive, lifelong medical care.
The test's development was supported by WSU’s Office of Commercialization, the Washington Research Foundation, and private donors. Beyond individual pet care, the test holds potential for broader applications in feline medicine, including pharmaceutical research and responsible breeding practices aimed at reducing CKD prevalence in future generations.
The availability of the FAIM test marks a significant advancement in predictive veterinary diagnostics and personalized pet care, reinforcing the growing role of genetics in preventive veterinary medicine.
